By Julian C. Hughes

ISBN-10: 0199596557

ISBN-13: 9780199596553

With extra humans on this planet dwelling into older age, Alzheimer's and different Dementias: The Facts takes a entire examine the unfold of dementia, and gives authoritative details and useful suggestion for victims, their households, and the doctors who deal with them.

Written via a expert in outdated age psychiatry, the ebook offers an outline of the entire varieties of dementia (including younger-onset dementias), from the most-recognized - Alzheimer's - to the less-frequent kinds, similar to these brought on by inherited metabolic problems or HIV. The e-book publications the reader step by step via how the mind works, and explains in transparent and easy language the impression of dementias at the mind, and the impression on an individual's cognitive function.

A committed bankruptcy explains how a prognosis is reached, together with different modes of evaluate, from blood exams performed by way of a GP, to professional scans, highlighting how the mind truly works. certain sections conceal the newest remedies to be had, together with the debatable use of antipsychotic drugs, and the potential for disease-modifying remedies within the future.

The ebook additionally explains how the multi-disciplinary workforce works jointly to appear after the sufferer's social wishes, equivalent to bathing and washing, in addition to their religious and palliative wishes. Alzheimer's and different Dementias: The Facts presents all of the correct info and suggestions for victims, family members and their care-givers to decide on the correct intervention on the correct time, to create - because the e-book advocates - a distinct and custom-made administration plan.

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Sample text

Meanwhile, there is an increasing mental deterioration too, which may itself be a result of inflammation in the brain. g. because they are immobile) and deteriorate both physically and mentally as a result—is common. 36 Chapter 4 · Alzheimer’s disease and mild cognitive impairment Criteria for a diagnosis of Alzheimer’s disease In 1984, following a working group of the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) and the Alzheimer’s Disease and Related Disorders Association (ADRDA), McKhann and his colleagues in the USA published criteria in the journal Neurology, to make the diagnosis of Alzheimer’s disease more uniform.

Hirano bodies The significance of these round bodies is not clear and they appear in normal brains as well as in other pathological conditions. They may also contain tau, among other things. Inflammatory changes There is evidence of inflammation—glial cells (see Chapter 2) such as astrocytes become active—around other areas of pathology, such as amyloid 42 Chapter 4 · Alzheimer’s disease and mild cognitive impairment plaques and NFTs, as well as in connection with vascular changes, for instance in the white matter of the brain.

Another way in which this definition now seems dated, perhaps, is that it leaves these points to the end almost as an afterthought. But, in fact, it is often these ‘non-cognitive’ symptoms and signs that cause people the most problems. Being forgetful is one thing, but changes in personality—becoming aggressive, for instance—are often much more devastating for the family carer. These behaviours are now often summarized as ‘behavioural and psychological symptoms of dementia’ (BPSD) and are increasingly being studied in their own right.

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Alzheimer's and other Dementias by Julian C. Hughes


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