By David Nutt, Liam Nestor

A part of the Oxford Psychiatry Library sequence, this pocketbook is a transparent and complete review of the mind technological know-how underpinning habit and the way this is helping clarify the present and destiny therapeutics for the diversity of addictions, utilizing complete color photos to augment figuring out. Addiction makes a speciality of the character of dependancy as a mind sickness that features a diversity of other behavioural characteristics akin to impulsivity and present dependence, and discusses the severe position of kinetic and pharmacological elements. The textual content explains how the first pharmacological ambitions of substances of abuse at the moment are understood, the relation to the variable nature of dependancy to diverse components, and the way this can result in new ways to remedy.

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Additional info for Addiction (Oxford Psychiatry Library)

Example text

Cancer recovery, cardiovascular rehabilitation). 1). Therefore, tobacco addiction still remains a major obstacle with respect to increasing the longevity of health and reducing the burden of tobacco-related diseases in populations across the world. Young people, aged 10–24 years, represent ∼27% of the world’s population. The health of young people, however, is largely neglected in global public health debate due to the perception that young people are healthy by virtue of their age. Compared to adults, however, people in adolescence are more likely to exhibit a number of psychological traits, such as risky and reward-seeking behaviour, that increase the potential likelihood of substance misuse and addiction.

Withdrawal from substances of abuse leads to repeated use. Craving for substances may occur following prolonged abstinence. Craving may trigger substance relapse. g. 1). Elements of addiction during the addiction trajectory are a reflection of changes in brain homeostasis. These homeostatic changes ultimately lead to: (1) a decreased sensitivity for natural rewards; (2) an enhanced sensitivity for conditioned substance cues and the expectation of substance use rewards; (3) a weakened control over substance use urges and substance-taking behaviour; and (4) substance tolerance and withdrawal.

Therefore, dopamine neurons in the VS are activated only when the current reward is better than the previous reward. Much evidence for the role of dopamine-dependent neural substrates in learning and memory comes from findings in associative learning. This is the process by which an 59 association between two stimuli (or a stimulus and behaviour) is learned. There are two forms of associative learning: classical and operant. In classical conditioning, a neutral stimulus is repeatedly paired with a reflex eliciting stimulus until the neutral stimulus elicits the same reflex response on its own.

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Addiction (Oxford Psychiatry Library) by David Nutt, Liam Nestor


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